Fig. 3

The development of maximal muscle strength and disease severity over the study course. A: Percentual distribution of the relative total muscle strength (rTFmax) comprising lower extremities (LE), upper extremities (UE), back and abdomen (abd), at time point 1 (t1, N = 70). B: Summary graphs of rTFmax (light grey) and the MADRS (white) scores over the study course (N = 50, p = < 0.001 after Tukey and Bonferroni correction, Friedman test (rTFmax), repeated measures ANOVA (MADRS)). Horizontal lines in boxplots represent median, dotted horizontal lines represent mean; boxes 25th and 75th quartiles; whiskers 5th and 95th percentiles; scatter plots show individual data points. Asterisks indicate significance level (*p < .05, **p < .01, ***p < .001)