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  1. Antidepressant efficacy is influenced by a multitude of factors, yet predicting treatment outcomes remains challenging. This difficulty is partly due to the commonly employed dichotomous classifications of tre...

    Authors: Haiping Tang, Yan Xia, Chenjie Gao, Yufan Cai, Yongqi Shao, Wenji Chen, Yonggui Yuan, Chunyu Liu, Zhijun Zhang and Zhi Xu
    Citation: BMC Psychiatry 2025 25:505
    Content type: Research Published on:

  3. Alzheimer’s disease (AD) and other dementias are major public health concerns with an increasing global impact. The burden of these conditions varies by region, age, and gender, and the COVID-19 pandemic has f...

    Authors: Dong-Ting Yu, Rui-Xuan Li, Jing-Ran Sun, Xue-Wen Rong, Xu-Guang Guo and Guo-Dong Zhu
    Citation: BMC Psychiatry 2025 25:503
    Content type: Research Published on:

  4. Locally validated measures are required for robust clinical and epidemiological assessments of anxiety symptoms and disorders. Few studies on the African continent have examined the psychometric properties of ...

    Authors: Leo Ziegel, Cristina Espinosa da Silva, Robert Bulamba, Alex Daama, Grace Kigozi, Amanda P. Miller, Godfrey Kigozi, Emmanuel Kyasanku, Stephen Mugamba, Anders Hammarberg, Anna Mia Ekström, Fred Nalugoda and Anna-Clara Hollander
    Citation: BMC Psychiatry 2025 25:502
    Content type: Research Published on:

  5. Over the last decade, there has been considerable development in precision psychiatry, especially in the development of novel prediction tools that can be used for early prediction of the risk of developing a ...

    Authors: Ivars Neiders, Signe Mežinska and Neeltje E. M. van Haren
    Citation: BMC Psychiatry 2025 25:501
    Content type: Systematic Review Published on:

  6. Depression is a leading cause of disability worldwide, significantly impacting global health, particularly for women. It accounts for 4.3% of the total disability-adjusted life years (DALYs), making it a major...

    Authors: Biazin Yenealem Mekuriaw, Alemayehu Molla, Misrak Negash, Tadese Teferi, Endashaw Habtamu, Mastewal Aschale and Aklile Tsega
    Citation: BMC Psychiatry 2025 25:500
    Content type: Research Published on:

  7. Despite parents of children treated for cancer commonly reporting psychological difficulties such as symptoms of depression and anxiety, there is a lack of evidence-based psychological interventions tailored t...

    Authors: Ella Thiblin, Johan Lundgren, Mattias Bergqvist, Tho Huynh, Christina Reuther, Sandra Rösler, Joanne Woodford and Louise von Essen
    Citation: BMC Psychiatry 2025 25:499
    Content type: Research Published on:

  9. Although reduced heart rate variability (HRV) has been observed in adolescents with major depressive disorder (MDD), substantial between-study heterogeneity and conflicting outcomes exist. Moreover, few studie...

    Authors: Wanlin Chen, Haisi Chen, Wenchen Jiang, Cheng Chen, Moya Xu, Haoxuan Ruan, Hang Chen, Zhenghe Yu and Shulin Chen
    Citation: BMC Psychiatry 2025 25:497
    Content type: Research Published on:

  10. Craving plays a central role in reinforcing alcohol use disorder (AUD), and non-invasive brain stimulation (NIBS) has shown potential as a therapeutic intervention in AUD. We aim to evaluate the efficacy and s...

    Authors: Dae Jin Kim, Hyunsuk Jeong, Su Yeon Kim, Young Hwa Kim and Hyeon Woo Yim
    Citation: BMC Psychiatry 2025 25:496
    Content type: Systematic Review Published on:

  11. Anxiety disorder is a significant concern in the context of mental health among Chinese high school students. Based on cross-sectional study and longitudinal study, this study constructed mediation models in o...

    Authors: Xianghe Chen, Yuxin Yang, Chenghao Zhong, Xinyu Zeng, Xiao Qiu, Xiangxiang Zhou, Chi Liu, Zhikai Tian, Bo Liu and Rongbin Yin
    Citation: BMC Psychiatry 2025 25:495
    Content type: Research Published on:

  12. Clinically stable inpatients with schizophrenia have generalized impairment of cognitive function along with abnormalities in renal function, but the link between cognitive function and renal function has been...

    Authors: Cong Cao, Xuehao Xu, Sumei Shen, Xiyan Bao, Fenglan Wang, Weishan Sun, Tao Gu, Lingling Hua, Chengbing Huang, Zhenlin Chen, Xuebin Qu and Aihua Zhou
    Citation: BMC Psychiatry 2025 25:494
    Content type: Research Published on:

  13. This study evaluated the utility of serum NR1 and NR2 concentrations in identifying individuals with first-episode schizophrenia (FES) and clinical high risk (CHR) as well as their correlations with clinical s...

    Authors: Zhen Mao, Feng Li, Lige Ge, Wenpeng Hou, Yushen Ding, Feifei Wang, Yujie Wen, Xueqi Wang, Yongying Cheng, Weiwei Hou, Lu Wang, Xinke Shi, Qijing Bo and Fang Dong
    Citation: BMC Psychiatry 2025 25:493
    Content type: Research Published on:

  14. Middle-aged  and elderly patients with cardiovascular disease (CVD) who have recovered from SARS-CoV-2 infection may experience depressive symptoms due to the physical and psychological impact of the pandemic.

    Authors: Zhenwei Dai, Xin Liu, Shu Jing, Hao Wang, Yiman Huang, Jiaqi Fu, Yijin Wu, Ling Zhang, Bicheng Han and Xiaoyou Su
    Citation: BMC Psychiatry 2025 25:492
    Content type: Research Published on:

  16. Borderline personality disorder (BPD) is highly correlated with other mental disorders and poses significant psychological and social risks both to individuals and to society. This study aims to investigate th...

    Authors: Mojdeh Askari, Mohammad Ali Zakeri, Alaa Hamza Hermis, Xiao Xu, Sri Widowati and Reza Mohammadmehr
    Citation: BMC Psychiatry 2025 25:490
    Content type: Research Published on:

  17. Emerging evidence has demonstrated a positive association of inflammation with depression. As an acute-phase reactant predominantly synthesized in hepatocytes, alpha-1-acid glycoprotein (AGP) serves as a sensi...

    Authors: Yuanyuan Zhong, Chunyue Fang, Tianliang Yao, Hongjin Wang and Min Jiang
    Citation: BMC Psychiatry 2025 25:489
    Content type: Research Published on:

  18. Early intervention services (EIS) for early psychosis can help reduce the patient-specific and economic impacts of mental illness, but they are underdeveloped and practices are poorly harmonized in many countr...

    Authors: Aurélie Schandrin, Julie Jourdan, Sihame Chkair, Sophie Bouvet, Pascale Fabbro-Peray and Mocrane Abbar
    Citation: BMC Psychiatry 2025 25:488
    Content type: Study Protocol Published on:

  19. Scales for the measurement of mental wellbeing and psychological distress are often used as if they measure different underlying concepts. This assumption is addressed in the present study by examining the dis...

    Authors: Leif Edvard Aarø, Marit Knapstad and Otto Robert Smith
    Citation: BMC Psychiatry 2025 25:487
    Content type: Research Published on:

  20. Mental disorders, one of the leading causes of the global health-related burden, which has been exacerbated by the emergence of the COVID-19 pandemic (2019–2021). In this study, we aim to provide global, regio...

    Authors: Yangyan Fan, Ahui Fan, Zhiping Yang and Daiming Fan
    Citation: BMC Psychiatry 2025 25:486
    Content type: Research Published on:

  21. This research builds on the understanding that low self-acceptance is an important feature of adolescent depression, and that social comparison is a critical factor in self-concept formation during adolescence...

    Authors: Qian-Nan Ruan, Guang-Hui Shen, Yu-Wei Wu, Dongwu Xu and Wen-Jing Yan
    Citation: BMC Psychiatry 2025 25:485
    Content type: Research Published on:

  22. Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have recently received Food and Drug Administration (FDA) approval for obesity management. However, the causal relationship between GLP-1RAs and psychiatric...

    Authors: Lingfeng Zhang, Xiang Chen, Yantao Xu, Jiachen Liu and Zhongchun Liu
    Citation: BMC Psychiatry 2025 25:484
    Content type: Research Published on:

  23. Major depressive disorder (MDD) is highly prevalent globally, significantly impacting psychological well-being (PWB). Herein, we aim to evaluate the impact of different living arrangements on PWB in individual...

    Authors: Chengxi Wen, Yifeng Liu, Yanzhi Li, Ruiying Chen, Hao Zhao, Xiaojuan Zhang, Xiaoxin Zhuang, Yuhua Liao, Jiejing Hao, Yan Chen, Wanxin Wang, Huiming Zhang, Lan Guo, Roger S. McIntyre, Kayla M. Teopiz, Ciyong Lu…
    Citation: BMC Psychiatry 2025 25:483
    Content type: Research Published on:

  24. This study established a network structure between problematic smartphone use (PSU) and poor sleep quality (PSQ) to explore their symptomatic relationship in adolescents with depression.

    Authors: Yongjie Zhou, Jian Gong, Jing Shao, Nan Yan, Linlin Meng, Kongliang He, Ying Shen, Qian Wei, Chunyan Zhang, Xuan Lei, Yuehua Cao and Yanni Wang
    Citation: BMC Psychiatry 2025 25:482
    Content type: Research Published on:

  25. Smartphone addiction is increasingly prevalent, particularly among younger individuals, and has been linked to poor sleep quality. This study aims to assess the effects of smartphone addiction, usage time, soc...

    Authors: Fedli Emre Kılıç, Osman Küçükkelepçe and Fatma Sena Konyalıoğlu
    Citation: BMC Psychiatry 2025 25:481
    Content type: Research Published on:

  26. Peer support roles within mental health services are rapidly increasing in number and scope in the UK and internationally. This paper explores the facilitators and barriers to delivering peer support effective...

    Authors: Una Foye, Natasha Lyons, Prisha Shah, Lizzie Mitchell, Karen Machin, Beverley Chipp, Stephen Jeffreys, Tamar Jeynes, Karen Persaud, Vicky Nicholls, Ruth E. Cooper, Andrew Grundy, Tamara Pemovska, Nafiso Ahmed, Rebecca Appleton, Julie Repper…
    Citation: BMC Psychiatry 2025 25:480
    Content type: Research Published on:

  27. Recent studies have suggested body mass index (BMI) change patterns in adulthood may be crucial for depression. This purpose of this study is to evaluate the impact of adult BMI change patterns on depression.

    Authors: Zhixiao Xu, Chengshui Chen and Xiong Lei
    Citation: BMC Psychiatry 2025 25:479
    Content type: Research Published on:

  28. Despite significant advances in AI-driven medical diagnostics, the integration of large language models (LLMs) into psychiatric practice presents unique challenges. While LLMs demonstrate high accuracy in cont...

    Authors: Dorit Hadar Shoval, Karny Gigi, Yuval Haber, Amir Itzhaki, Kfir Asraf, David Piterman and Zohar Elyoseph
    Citation: BMC Psychiatry 2025 25:478
    Content type: Research Published on:

  29. To analyze the symptoms, courses, and severities of depressive disorder, as well as the morphological changes in the spleens and related immune mechanisms, we recruited patients with first-episode or recurrent...

    Authors: Zouqing Lin, Xiaoyan Xu, Kai Zhang, Tenglong Wang, Leiming Cao, Zhiqiang Wang and Guoqiang Wang
    Citation: BMC Psychiatry 2025 25:477
    Content type: Research Published on:

  30. Bright light therapy (BLT) has been proved to have beneficial effects on Parkinson’s disease (PD), the mechanisms remained unclear. Improvements of visual pathways might be key to BLT.

    Authors: Wei-ye Xie, Hui Lou, Jia-ying Liu, Jie-yun Yin, Tian-qi Zhang, Cheng-jie Mao, Fen Wang, Chun-feng Liu and Yun Shen
    Citation: BMC Psychiatry 2025 25:476
    Content type: Research Published on:

  32. Bilateral anterior capsulotomy and deep brain stimulation (DBS) of the nucleus accumbens (NAc) represent investigational treatment options for severe, treatment-refractory anorexia nervosa (AN). However, follo...

    Authors: Fengting Wang, Wei Liu, Halimureti Paerhati, Zhengyu Lin, Kuanghao Ye, Lulin Dai, Tao Wang, Zhaohui Lan, Dianyou Li, Yijie Lai, Bomin Sun and Shikun Zhan
    Citation: BMC Psychiatry 2025 25:474
    Content type: Research Published on:

  33. Individuals with severe mental illness (SMI) are at risk of early-onset frailty, leading to adverse outcomes. Effective interventions for reducing frailty in this population are currently lacking.

    Authors: Urska Arnautovska, Rebecca Soole, Winona Wing Ling Kwan, Natasha Reid, Andrea Baker, Emily H. Gordon, Ruth E. Hubbard, Dan Siskind and Nicola Warren
    Citation: BMC Psychiatry 2025 25:473
    Content type: Research Published on:

  34. The stress-is-enhancing mindset has beneficial effects on physical, psychological, and emotional well-being. However, its association with internet gaming disorder (IGD) had not been investigated. By integrati...

    Authors: Haiyan Xiang, Lijing Liu, Xin Su, Ying Yang, Haifeng Xue, Bo Liu, Yanling Tu, Ruxin Wang, Xinxin Mo, Hongye Luo, Lijuan Li, Xianzhang Tian, Yanjie Yang, Zhengxue Qiao, Liping Li, Tong Xie…
    Citation: BMC Psychiatry 2025 25:472
    Content type: Research Published on:

  35. To evaluate the success rate of different antidepressants in addressing depression among teenagers, while also offering substantiation for the efficacy and tolerability of these treatments in this demographic.

    Authors: Tianwei Wu, Fan Song, Weili Cao, Chengjiang Liu and Shuangzhen Jia
    Citation: BMC Psychiatry 2025 25:471
    Content type: Systematic Review Published on:

  36. Insomnia is a prevalent yet under-characterized disorder, particularly regarding the heterogeneity of patients and their associated responses to different treatment modalities. This often leads to suboptimal m...

    Authors: Si-Jing Chen, Hans Ivers, Thien Thanh Dang-Vu, Colin M. Shapiro, Colleen E. Carney, Rébecca Robillard and Charles M. Morin
    Citation: BMC Psychiatry 2025 25:470
    Content type: Study Protocol Published on:

  37. Suicidal ideation (SI) is one of the strongest predictors of suicide attempts, yet reliable prediction models for suicide risk remain scarce. A key challenge is that SI can fluctuate over time, potentially ref...

    Authors: Stephanie Homan, Zachary Roman, Anja Ries, Prabhakaran Santhanam, Sofia Michel, Anna-Marie Bertram, Nina Klee, Carlo Berther, Sarina Blaser, Marion Gabi, Philipp Homan, Hanne Scheerer, Michael Colla, Stefan Vetter, Sebastian Olbrich, Erich Seifritz…
    Citation: BMC Psychiatry 2025 25:469
    Content type: Research Published on:

  38. This study explores the relationships among chronotype, sensation seeking, sleep quality and depressive symptoms in adolescents with diagnosed depression, aiming to clarify the mechanisms by which chronotype i...

    Authors: Fangyi Wang, Ying Zhou, Xiao Hou, Shifen Ni, Xiaodi Xia, Tanwei Zhang, Yunyan Zhang, Xiangyu Li, Keyi Wen, Yutong Wang, Wenfen Zhu and Yixiao Fu
    Citation: BMC Psychiatry 2025 25:468
    Content type: Research Published on:

  39. Antipsychotic medications are crucial for alleviating symptoms of schizophrenia (SCZ). However, treatment responses vary across individuals, and few reliable biomarkers currently exist to predict the clinical ...

    Authors: Mengyi Luo, Suzhen Zhang, Jingxin Xue, Tianhao Gao, Xuan Li, Zhaolin Zhai, Chang Lu, Yuke Dong, Kaiming Zhuo, Qiong Xiang, Qing Kang, Shunying Yu, Chunhong Shao and Dengtang Liu
    Citation: BMC Psychiatry 2025 25:467
    Content type: Research Published on:

  40. Accurate detection of schizophrenia poses a grand challenge as a complex and heterogeneous mental disorder. Current diagnostic criteria rely primarily on clinical symptoms, which may not fully capture individu...

    Authors: Jie Huang, Yanli Zhao, Zhanxiao Tian, Wei Qu, Xia Du, Jie Zhang, Meng Zhang, Yunlong Tan, Zhiren Wang and Shuping Tan
    Citation: BMC Psychiatry 2025 25:466
    Content type: Research Published on:

  41. In the Netherlands, maintaining high standards of mental healthcare faces challenges due to an increasing demand for mental healthcare and a focus on symptomatic recovery rather than personal growth and improv...

    Authors: Thijs Beckers and Martijn Koopmans
    Citation: BMC Psychiatry 2025 25:465
    Content type: Research Published on:

  42. Red blood cell distribution width (RDW)-to-albumin ratio (RAR) is a novel index. Its relationship with depression, a common and complex psychiatric disorder, remains unclear. This study utilized the National H...

    Authors: Yao Zhou, Lijuan Zhao, Yunzhu Tang and Shuxia Qian
    Citation: BMC Psychiatry 2025 25:464
    Content type: Research Published on:

  43. The aim of the current study is to examine the relationship between nonsuicidal self-injury (NSSI) and resilience. Resilience has been identified as a critical area for further investigation in the context of ...

    Authors: Daphne Weedage, Nienke Kool-Goudzwaard, Dwayne Meijnckens, Robert R. J. M. Vermeiren and Cyril Boonmann
    Citation: BMC Psychiatry 2025 25:463
    Content type: Systematic Review Published on:

  44. Studies have reported that white matter hyperintensities (WMHs) are associated with disturbances in immune function, and the relationship between WMHs and cognitive impairments have been documented in various ...

    Authors: Yan Zhang, Xiuxia Yuan, Yu Zhang, Yishao Chen, Keju Su, Kangkang Xue, Suying Ding, Jingfeng Chen, Xiaoduo Fan and Xueqin Song
    Citation: BMC Psychiatry 2025 25:462
    Content type: Research Published on:

  45. The 2023 Kahramanmaraş earthquakes resulted in extensive destruction, significant loss of life, and widespread displacement, with Hatay province being the most severely affected region. Earthquake survivors re...

    Authors: Ertan Yilmaz and Mehmet Erdem
    Citation: BMC Psychiatry 2025 25:461
    Content type: Research Published on:

  46. Relatives/friends (carers) of people who are involuntarily admitted to a psychiatric hospital report high levels of stress, feelings of isolation and exclusion from their patient’s care. One-to-one peer suppor...

    Authors: Imogen Wells, Kelly Wintsch, Abigail G-Medhin, Brynmor Lloyd-Evans, Steve Gillard, Rose McCabe, Mohamed Yaasir Mohamudbucus, Candelaria Mahlke, Katharina Nagel, Zhenreenah Muhxinga, Swaran Singh, Stefan Priebe and Domenico Giacco
    Citation: BMC Psychiatry 2025 25:460
    Content type: Research Published on:

  47. The aim of this study was to investigate physiological differences in electrolytes and complete blood counts in adolescent patients with depression with and without psychotic symptoms. By comparing baseline da...

    Authors: Xinyuan Li, Ziming Liu, Yanming Li, Xiuyu Jin, Shumin Zhu, Zining Liu, Xintong Pang and Yulan Geng
    Citation: BMC Psychiatry 2025 25:459
    Content type: Research Published on:

  48. Seasonal disturbances were common in mood disorders patients. The global seasonality score (GSS), derived from the Seasonal Pattern Assessment Questionnaire (SPAQ), was widely used to assess seasonality and re...

    Authors: Chiao-Erh Chang, Hsi-Chung Chen, I.-Ming Chen, Cheng-Dien Hsu, Chih-Ming Liu, Chun-Hsin Chen, Tsung-Yang Wang, Wen-Yin Chen, Shiau-Shian Huang, Yen-Chih Chen and Po-Hsiu Kuo
    Citation: BMC Psychiatry 2025 25:458
    Content type: Research Published on:

  49. After the official end of the dynamic zero-COVID policy in China, healthcare workers continued to heavy workloads and psychological stress. In this new phase, concerns related to work and family, rather than i...

    Authors: Chao Zhang, Ruyong Li, Wei Zhang, Yanqiang Tao, Xiangping Liu and Yichao Lv
    Citation: BMC Psychiatry 2025 25:457
    Content type: Research Published on:

  50. The COVID-19 pandemic has posed challenges to healthcare systems worldwide. For healthcare workers (HCW), an increased prevalence of mental distress and the impact of various resources have been identified. Ps...

    Authors: Sabine Mogwitz, Gloria-Beatrice Wintermann, Christian Albus, Andreas M. Baranowski, Petra Beschoner, Yesim Erim, Franziska Geiser, Lucia Jerg-Bretzke, Eva Morawa, Susann Steudte-Schmiedgen and Kerstin Weidner
    Citation: BMC Psychiatry 2025 25:456
    Content type: Research Published on:
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BMC Psychiatry

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