Table 4 Point-biserial Pearson correlations demonstrating the relationship between each continuous variable and the addition of IR medication at 90 days. Treatment responses representing a change in score between baseline and 90 days were Z-transformed prior to analysis
Variable Group | Variable | Description | Pearson correlation coefficient (r) | R2 | p |
|---|---|---|---|---|---|
Demographics | Age | Age in Years | 0.02 | 0.00032 | 0.716 |
ER Prescription Decision | Tendency to Prescribe ER | Integer Value: % of patients with an ER prescription | − 0.10 | 0.0090 | 0.07 |
Time in Treatment Prior to ER | Integer Value | − 0.05 | 0.0023 | 0.33 | |
Assessment scores at baseline | ASSET | ADHD symptoms in terms of daily life functioning impact at the time of visit | 0.050 | 0.0025 | 0.31 |
PHQ-9 | Severity of depressive symptoms in terms of frequency at the time of visit | − 0.03 | 0.00096 | 0.53 | |
GAD-2 | Severity of anxious symptoms in terms of frequency at the time of visit | − 0.05 | 0.0028 | 0.28 | |
CGI-S | Global severity of the overall presentation assessed by the clinician at the time of visit | − 0.05 | 0.0023 | 0.34 | |
CGI-I | Global improvement of the overall presentation assessed by the clinician | − 0.14 | 0.020 | 0.01 | |
Assessment scores at 90 daysa | ASSET | Severity of ADHD symptoms in terms of daily life functioning impact | − 0.03 | 0.00063 | 0.62 |
PHQ-9 | Severity of depressive symptoms in terms of frequency | − 0.00 | 0.000004 | 0.96 | |
GAD-2 | Severity of anxious symptoms in terms of frequency | 0.04 | 0.0013 | 0.47 | |
CGI-S | Global severity of the overall presentation assessed by the clinician | − 0.04 | 0.0014 | 0.45 | |
|  | CGI-I | Global improvement of the overall presentation assessed by the clinician | − 0.10 | 0.0096 | 0.06 |
Treatment response (Change in clinical assessments from baseline to 90 daysa) | Change in ASSET | Change of severity of ADHD symptoms in terms of daily life functioning impact | 0.09 | 0.0074 | 0.08 |
Change in PHQ-9 | Change of severity of depressive symptoms | − 0.03 | 0.0011 | 0.50 | |
Change in GAD-2 | Change of severity of anxiety symptoms | − 0.09 | 0.0083 | 0.06 | |
Change in CGI-S | Change of global severity of the overall presentation assessed by the clinician | − 0.05 | 0.00086 | 0.34 |