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Table 4 The association between inflammatory markers and depressive symptoms in obese population

From: Systemic inflammation as a mediator in the link between obesity and depression: Evidence from a nationwide cohort study

 

Model I

Model II

Model III

 

OR (95%CI)

P-value

OR (95%CI)

P-value

OR (95%CI)

P-value

Total

NLR

1.1 (1.05,1.16)

 < 0.001

1.12 (1.06,1.17)

 < 0.001

1.08 (1.02,1.14)

0.005

SIRI

1.14 (1.07,1.21)

 < 0.001

1.18 (1.11,1.26)

 < 0.001

1.12 (1.05,1.2)

0.001

SII (per 100 units)

1.05 (1.03,1.07)

 < 0.001

1.04 (1.03,1.06)

 < 0.001

1.03 (1.01,1.05)

0.001

Male

NLR

1.19 (1.11,1.28)

 < 0.001

1.19 (1.10,1.28)

 < 0.001

1.17 (1.08,1.26)

 < 0.001

SIRI

1.25 (1.14,1.36)

 < 0.001

1.24 (1.13,1.36)

 < 0.001

1.19 (1.08,1.31)

 < 0.001

SII (per 100 units)

1.08 (1.05,1.11)

 < 0.001

1.07(1.05,1.10)

 < 0.001

1.06 (1.03,1.10)

 < 0.001

Female

NLR

1.08 (1.01,1.15)

0.026

1.08 (1.01,1.15)

0.019

1.02 (0.95,1.10)

0.556

SIRI

1.15 (1.06,1.25)

0.001

1.16 (1.06,1.26)

0.001

1.09 (0.99,1.19)

0.067

SII (per 100 units)

1.03 (1.01,1.05)

0.003

1.03 (1.01,1.05)

0.005

1.01 (0.99,1.04)

0.220

  1. Abbreviation: OR Odds ratio, CI Confidence interval
  2. Crude Model: no covariates were adjusted
  3. Model I: adjusted for age, sex
  4. Model II: adjusted for age, sex, race, diabetes mellitus, hypertension, poverty income ratio, and serum creatinine levels