Serum NR1 and NR2 concentrations in first-episode schizophrenia and clinical high-risk for psychosis

BMC Psychiatry

Table 2 Comparison of MCCB domain scores among the FES, CHR and HC groups

MCCB Domains	FES	CHR	HC	Statistic^a		Pairwise comparison^b
MCCB Domains	FES	CHR	HC	F	P		P	*Effect size*^c
Speed of Processing	32.14 ± 8.80	40.34 ± 9.22	44.54 ± 8.23	15.55	< 0.001	FES < CHR	0.001	0.91
Speed of Processing	32.14 ± 8.80	40.34 ± 9.22	44.54 ± 8.23	15.55	< 0.001	FES < HC	< 0.001	1.46
Attention/Vigilance	31.00 ± 10.07	42.28 ± 11.48	43.82 ± 9.21	14.32	< 0.001	FES < CHR	< 0.001	1.05
Attention/Vigilance	31.00 ± 10.07	42.28 ± 11.48	43.82 ± 9.21	14.32	< 0.001	FES < HC	< 0.001	1.33
Working memory	36.88 ± 9.81	35.61 ± 17.37	44.74 ± 7.92	2.64	0.08	FES < HC	0.04	0.89
Verbal learning	38.63 ± 9.89	43.62 ± 11.03	47.95 ± 10.37	4.15	0.02	FES < HC	0.006	0.92
Visual learning	37.31 ± 15.52	44.73 ± 11.34	43.87 ± 10.81	5.83	0.004	FES < CHR	0.002	0.55
Visual learning	37.31 ± 15.52	44.73 ± 11.34	43.87 ± 10.81	5.83	0.004	FES < HC	0.008	0.50
Reasoning/problem solving	32.57 ± 9.70	40.12 ± 12.92	40.21 ± 9.80	8.76	< 0.001	FES < CHR	< 0.001	0.67
Reasoning/problem solving	32.57 ± 9.70	40.12 ± 12.92	40.21 ± 9.80	8.76	< 0.001	FES < HC	< 0.001	0.78
Social recognition	34.59 ± 11.23	37.39 ± 9.43	36.41 ± 11.53	0.13	0.88	—	—	—
Total	35.15 ± 5.82	41.46 ± 9.26	43.08 ± 6.05	12.88	< 0.001	FES < CHR	0.001	0.84
Total	35.15 ± 5.82	41.46 ± 9.26	43.08 ± 6.05	12.88	< 0.001	FES < HC	< 0.001	1.34

^aMultivariate analysis of covariance
^bPost-hoc Bonferroni correction
^cEffect size was calculated using Cohen’s d for significant pairwise comparisons

ISSN: 1471-244X