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Emerging evidence has demonstrated a positive association of inflammation with depression. As an acute-phase reactant predominantly synthesized in hepatocytes, alpha-1-acid glycoprotein (AGP) serves as a sensi...
Mental disorders, one of the leading causes of the global health-related burden, which has been exacerbated by the emergence of the COVID-19 pandemic (2019–2021). In this study, we aim to provide global, regio...
This research builds on the understanding that low self-acceptance is an important feature of adolescent depression, and that social comparison is a critical factor in self-concept formation during adolescence...
Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have recently received Food and Drug Administration (FDA) approval for obesity management. However, the causal relationship between GLP-1RAs and psychiatric...
Major depressive disorder (MDD) is highly prevalent globally, significantly impacting psychological well-being (PWB). Herein, we aim to evaluate the impact of different living arrangements on PWB in individual...
This study established a network structure between problematic smartphone use (PSU) and poor sleep quality (PSQ) to explore their symptomatic relationship in adolescents with depression.
Smartphone addiction is increasingly prevalent, particularly among younger individuals, and has been linked to poor sleep quality. This study aims to assess the effects of smartphone addiction, usage time, soc...
Peer support roles within mental health services are rapidly increasing in number and scope in the UK and internationally. This paper explores the facilitators and barriers to delivering peer support effective...
Recent studies have suggested body mass index (BMI) change patterns in adulthood may be crucial for depression. This purpose of this study is to evaluate the impact of adult BMI change patterns on depression.
Despite significant advances in AI-driven medical diagnostics, the integration of large language models (LLMs) into psychiatric practice presents unique challenges. While LLMs demonstrate high accuracy in cont...
To analyze the symptoms, courses, and severities of depressive disorder, as well as the morphological changes in the spleens and related immune mechanisms, we recruited patients with first-episode or recurrent...
Bright light therapy (BLT) has been proved to have beneficial effects on Parkinson’s disease (PD), the mechanisms remained unclear. Improvements of visual pathways might be key to BLT.
Non-suicidal self-injury (NSSI) represents a significant public health concern, particularly among adolescents. Understanding the prevalence of NSSI within specific at-risk populations, such as athletes, is cr...
Bilateral anterior capsulotomy and deep brain stimulation (DBS) of the nucleus accumbens (NAc) represent investigational treatment options for severe, treatment-refractory anorexia nervosa (AN). However, follo...
Individuals with severe mental illness (SMI) are at risk of early-onset frailty, leading to adverse outcomes. Effective interventions for reducing frailty in this population are currently lacking.
The stress-is-enhancing mindset has beneficial effects on physical, psychological, and emotional well-being. However, its association with internet gaming disorder (IGD) had not been investigated. By integrati...
To evaluate the success rate of different antidepressants in addressing depression among teenagers, while also offering substantiation for the efficacy and tolerability of these treatments in this demographic.
Insomnia is a prevalent yet under-characterized disorder, particularly regarding the heterogeneity of patients and their associated responses to different treatment modalities. This often leads to suboptimal m...
Suicidal ideation (SI) is one of the strongest predictors of suicide attempts, yet reliable prediction models for suicide risk remain scarce. A key challenge is that SI can fluctuate over time, potentially ref...
This study explores the relationships among chronotype, sensation seeking, sleep quality and depressive symptoms in adolescents with diagnosed depression, aiming to clarify the mechanisms by which chronotype i...
Antipsychotic medications are crucial for alleviating symptoms of schizophrenia (SCZ). However, treatment responses vary across individuals, and few reliable biomarkers currently exist to predict the clinical ...
Accurate detection of schizophrenia poses a grand challenge as a complex and heterogeneous mental disorder. Current diagnostic criteria rely primarily on clinical symptoms, which may not fully capture individu...
In the Netherlands, maintaining high standards of mental healthcare faces challenges due to an increasing demand for mental healthcare and a focus on symptomatic recovery rather than personal growth and improv...
Red blood cell distribution width (RDW)-to-albumin ratio (RAR) is a novel index. Its relationship with depression, a common and complex psychiatric disorder, remains unclear. This study utilized the National H...
The aim of the current study is to examine the relationship between nonsuicidal self-injury (NSSI) and resilience. Resilience has been identified as a critical area for further investigation in the context of ...
Studies have reported that white matter hyperintensities (WMHs) are associated with disturbances in immune function, and the relationship between WMHs and cognitive impairments have been documented in various ...
The 2023 Kahramanmaraş earthquakes resulted in extensive destruction, significant loss of life, and widespread displacement, with Hatay province being the most severely affected region. Earthquake survivors re...
Relatives/friends (carers) of people who are involuntarily admitted to a psychiatric hospital report high levels of stress, feelings of isolation and exclusion from their patient’s care. One-to-one peer suppor...
The aim of this study was to investigate physiological differences in electrolytes and complete blood counts in adolescent patients with depression with and without psychotic symptoms. By comparing baseline da...
Seasonal disturbances were common in mood disorders patients. The global seasonality score (GSS), derived from the Seasonal Pattern Assessment Questionnaire (SPAQ), was widely used to assess seasonality and re...
After the official end of the dynamic zero-COVID policy in China, healthcare workers continued to heavy workloads and psychological stress. In this new phase, concerns related to work and family, rather than i...
The COVID-19 pandemic has posed challenges to healthcare systems worldwide. For healthcare workers (HCW), an increased prevalence of mental distress and the impact of various resources have been identified. Ps...
This study aimed to analyse the differences in creative thinking dispositions between patients with bipolar disorder (BD) and healthy controls (HCs) and to examine the potential role of cognitive flexibility (...
Attention deficit hyperactivity disorder (ADHD) and Obstructive sleep apnea (OSA) are highly clinically co-occurring, but the mechanisms behind this remain unclear, so this article analyzes the reasons for the...
Alcohol craving and relapse occur after the reactivation of alcohol reward memory. Previous studies suggest that drug-associated memory undergoes reconsolidation once retrieved by drug-associated stimuli. This...
The Correction to this article has been published in BMC Psychiatry 2025 25:595
Outpatient psychotherapies are gold standard interventions for borderline personality disorder (BPD); however, in clinical reality, higher rates of psychiatric hospitalization and more severe symptoms, includi...
This study aimed to assess the association between sedentary behavior (SB) and dementia among the general adult population.
Nurses are the front-liners for patients who need urgent care; therefore, they are exposed to several stressors. Indirect exposure to others’ trauma is called secondary traumatic stress. This study examined th...
Obesity and depression are major public health issues with a complex, bidirectional relationship potentially involving systemic inflammation.
Obsessive‒compulsive personality disorder (OCPD) is characterized by a rigid need for control, orderliness, and perfectionism, often impairing functionality. Traits such as striving for an "ideal" figure can l...
Recent neurophysiological studies showed that patients with psychiatric disorders demonstrated abnormalities in sensorimotor functions in addition to cognitive deficits. These findings intrigued us to investig...
Migration has extensive consequences on socioeconomic and health status among older adults at the place of destination; various factors in the migration process affect mental health, a prominent social determi...
Major Depressive Disorder (MDD) has a 50–80% recurrence rate highlighting the urgent need for more efficient recurrence prevention programs. Currently, recurrences are often identified too late, while existing...
Fibromyalgia frequently coexists with psychiatric disorders, creating complex challenges in managing the health and quality of life for affected individuals. Existing literature points to significant overlap b...
The aim of this study is to investigate the characteristics of gut microbiota in depression and anxiety through a systematic review.
Croatia is one of the European Union (EU) countries where low-dose codeine products (LDCP) can be purchased over the counter (OTC) directly from community pharmacists without a prescription. The misuse and dep...
Repetitive transcranial magnetic stimulation (rTMS) is an effective treatment for major depressive disorder (MDD) with a low incidence of adverse effects. However, bradycardia is not commonly recognized as an ...
Autism is a neurodevelopmental condition more prevalent in males, with sex differences emerging in both prevalence and core symptoms. However, most studies investigating behavioral and cognitive features of au...
Schizophrenia is one of the mental disorders with the longest delay in treatment. Motivation for help-seeking is an important factor in getting professional treatment. There is no instrument to measure help-se...
Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder that begins in childhood and often persists into adulthood, characterized by difficulties with attention, impulsivity, and hyper...
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