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Childhood trauma (CT) is common in first episode schizophrenia (FES), affecting prognosis and functionality. However, the mechanisms by which CT effects prognosis are not clear. This study aimed to investigate...
Despite being a widely used and recommended measure of functioning, the Columbia Impairment Scale (CIS) lacks consensus on scale structure and whether child- and parent-report versions measure the same constru...
Bipolar disorder (BD) is a common mental disorder characterized by significant cognitive dysfunction, the mechanisms of which remain unclear. Oxidative stress and glial cell line-derived neurotrophic factor (G...
The theory of complexity loss in neurodivergent brain is widely acknowledged. However, the findings of autism research do not seem to align well with this theory. We aim to investigate the brain complexity in ...
The mental health of mental health care professionals has become a key area of research due to the increasing demands and stressors inherent in the work environment. This study explored the relationship betwee...
Major depressive disorder (MDD) is a common and debilitating cause of disability worldwide. Recently, it has been suggested that individualized goal setting may play a role in patient-centered recovery. This s...
Mental health conditions represent a significant global public health issue, affecting millions of people worldwide. To meet the increasing demands on mental health services in Switzerland, the development of ...
Accurately diagnosing Anxiety-Depression Comorbidity Syndrome in Gastroenterology Inpatients (ADCS-GI) shows significant challenges as traditional diagnostic methods fail to meet expectations due to patient he...
Decreased physical activity and overnutrition among adolescents have become important public health problems shared by countries around the world. In addition, the prevalence of psychological symptoms among ad...
Substance use and traumatic events are prevalent in Afghanistan, but their relationship is under-investigated.
Patients experiencing a mental health crisis often present to the emergency department and are admitted to an inpatient facility for treatment. This can cause incontinuity in care, increased costs, and may wor...
This feasibility study evaluated adherence and effectiveness to a digital multimodal intervention (cognitive and physical training) for cancer-related cognitive impairment (CRCI) in patients with breast cancer.
Post-stroke depression (PSD) constitutes an important complication of stroke, affecting approximately one-third of stroke patients. PSD decreases rehabilitation motivation, delays function recovery, and increa...
Depression in late-life is linked to an increased risk of Alzheimer’s dementia (AD), with the risk potentially varying according to the age at onset of depression. Previous studies have typically dichotomized ...
Understanding factors influencing the use of coercive practices in clinical psychiatry is necessary to develop strategies to reduce their use. However, there is little evidence regarding staff perceptions of s...
Rumination is regarded as a cognitive risk factor and a focal point of clinical interventions aimed at mitigating suicidal ideation. Nonetheless, the mechanisms how rumination affects suicidal ideation warrant...
Understanding the differences between various instruments for assessing depression will help researchers and health practitioners to choose a more appropriate tool and develop a framework to enhance resilience...
Growing evidence indicates a link between insulin resistance and post-stroke depression (PSD). This study employed the triglyceride glucose (TyG) index as a measure of insulin resistance to investigate its rel...
The pathophysiological mechanisms of schizophrenia are complex and not fully elucidated. This study aimed to investigate changes to total glutathione (T-GSH), glutathione disulfide (GSSG), reduced glutathione ...
The mental health burden among adolescents has been increasing, impacting individuals even before formal diagnosis of common mental disorders. Although personality traits, as key indicators of mental health co...
Schizophrenia, a severe mental disorder with complex pathophysiology, involves neurotrophic factors, which play crucial roles in neurodevelopment and neuroplasticity. This study investigated NGF-β and BDNF lev...
Medication nonadherence is a prevalent issue among patients with bipolar disorder, leading to substantial negative consequences. Despite documented cognitive deficits in this population, the relationship betwe...
Dysthymia, a chronic depressive disorder, poses a significant public health challenge due to its prolonged course and substantial impact on quality of life, particularly among high-risk populations such as you...
Nearly 20% of women will be confronted with anxiety or depressive disorders during the perinatal period and this may lead to adverse outcomes for both mother and child. Cognitive behavioural therapy (CBT) is t...
Russia’s full-scale military invasion of Ukraine on February 24, 2022 led to an increase of anxiety and depressive states, psychosomatic manifestations, and a tendency to abuse alcohol and psychoactive substan...
Individuals with obsessive-compulsive disorder (OCD) face both personal and system-based barriers in receiving first-line treatment, i.e. cognitive behavioral therapy (CBT) with exposure and response preventio...
Most research in children with ADHD has focused on risk factors and their outcomes, such as symptom severity as a risk factor for functional impairment. Yet, a small group of studies show that some children fu...
The 686 Program in China primarily aims to provide certain health and policy services to individuals with severe mental disorders within the community. As of 2020, a total of 6.43 million patients were registe...
Long-acting injectable antipsychotics (LAIs) reduce relapses in schizophrenia; however, most clinicians reserve LAIs for nonadherence with oral antipsychotics (OAs) or severe disease.
Schizophrenia is a severe mental health condition with high impact on those affected and their families. Community-based rehabilitation (CBR) is a recommended treatment component for schizophrenia in low- and ...
Anxiety disorders are increasing worldwide, untreated anxiety is linked to maternal and child health outcomes. The purpose of this study is to test psychometric properties of the Perinatal Anxiety Screening Sc...
Depression and anxiety were not only common but also with serious consequence in infertility patients. The current study endeavors to define distinct depression and anxiety profiles of infertility patients and...
The relationship between obesity and mental health has attracted attention. However, large sample studies on the relationship between visceral fat obesity and depression are lacking. This study aimed to explor...
Bus drivers face complex work challenges and high infection risks, particularly heightened during the COVID-19 pandemic, which significantly affects their mental health. This study used network analysis to con...
The prevalence of mental illness in Taiwan increased. Identifying and mitigating risk factors for mental illness is essential. Inflammation may be a risk factor for mental illness; however, the predictive powe...
Neuroinflammatory processes are directly involved in the pathogenesis of non-suicidal self-injury (NSSI) among adolescents. However, their role in predicting the outcome of adolescent NSSI is unknown. This stu...
Self-affirmation, a crucial concept that promotes self-esteem and individual development amidst life challenges, has proven therapeutic, preventative, and enhancing benefits. However, there is limited understa...
The elevated prolactin levels in first-episode drug-naïve (FEDN) schizophrenia patients may correlate with long-term stress caused by childhood trauma. This study aimed to assess the relationship between eleva...
In a study involving 831 women and 309 men aged 18 to 64, we sought to explore the key determinants influencing various components of well-being, including happiness, life satisfaction, and vigor/vitality. The...
Care providers working with adolescents with anorexia nervosa (AN) encounter difficulties inherent in the illness (denial, ambivalence) and those related to the fact that it is most often the parents who bring...
Mental healthcare for people with a severe mental illness (SMI) is increasingly being delivered in a deinstitutionalized setting. Community-dwelling, ambulatory care and support, and the associated treatment g...
Cognitive impairment and depressive symptoms are prevalent and closely interrelated mental health issues in the elderly. Traditional methods for identifying depressive symptoms in this population often lack ef...
Mental disorders are a major public health issue, causing 4.9% of global disability-adjusted life years (DALYs). In Jordan, factors like regional conflicts, economic changes, and population growth contribute t...
Adolescent suicide is a major public health concern; therefore, this study evaluated the factors related to suicide risk in adolescents.
The prevalence of mental disorders is gradually increasing in China. As the Chinese government fully implements the tiered diagnosis and treatment system, community health service centers will take on an incre...
Treatment-resistant depression (TRD) in major depressive disorder (MDD) is defined as the failure of two or more antidepressants. Few studies have characterized the natural history and treatment patterns of th...
The semantic processing deficit stands as a central feature of cognitive abnormalities in schizophrenia. Both transcranial direct current stimulation (tDCS) and retrieval practice have been demonstrated as ext...
Several studies have indicated a potential association between obesity, depression, and sleep disorders. However, the role of depression in mediating the relationship between obesity and sleep disorders remain...
Changes in cognitive impairments and their relationship with psychopathological symptoms during treatment in schizophrenia remain debatable. Especially, there is few studies specifically focusing on female pat...
The development of schizophrenia is related to a combination of genetic and epigenomic factors. MicroRNAs (miRNAs) play a crucial role in epigenetic processes and are relevant to the onset and progression of s...
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